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Literature summary for 3.2.1.39 extracted from

  • Gissibl, A.; Care, A.; Parker, L.M.; Iqbal, S.; Hobba, G; Nevalainen, H.; Sunna, A.
    Microwave pretreatment of paramylon enhances the enzymatic production of soluble beta-1,3-glucans with immunostimulatory activity (2018), Carbohydr. Polym., 196, 339-347 .
    View publication on PubMed
Search for more literature for 3.2.1.39

Activating Compound

Activating Compound Comment Organism Structure
additional information hydrothermal microwave pretreatment of substrate paramylon at 170°C for 2 min is established to facilitate and enhance the enzymatic production of soluble bioactive beta-1,3-glucans from the recalcitrant substrate paramylon, structure comparisons of paramylon granules with and without heat treatment, overview. Virtual absence of enzymatic hydrolysis of paramylon pretreated at the lower incubation temperatures may be explained by steric hindrance of the enzymes Helix pomatia

Application

Application Comment Organism
pharmacology action of endo-beta-1,3-glucanase on the microwave-pretreated paramylon produces soluble beta-1,3-glucans with degrees of polymerisation (DP) ranging from 2-59. The hydrolysis products induce TNFalpha production exhibiting an immunostimulatory effect on murine J774 macrophages Helix pomatia

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
paramylon + H2O Helix pomatia
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Helix pomatia
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information hydrothermal microwave pretreatment of substrate paramylon at 170 °C for 2 min is established to facilitate the enzymatic production of soluble bioactive beta-1,3-glucans from the recalcitrant substrate paramylon, structure comparisons of paramylon granules with and without heat treatment, overview. Virtual absence of enzymatic hydrolysis of paramylon pretreated at the lower incubation temperatures may be explained by steric hindrance of the enzymes Helix pomatia ?
-
 ?
paramylon + H2O
-
 Helix pomatia ?
-
 ?
paramylon + H2O action of endo-beta-1,3-glucanase on the microwave-pretreated paramylon produces soluble beta-1,3-glucans with degrees of polymerisation (DP) ranging from 2-59 Helix pomatia ?
-
 ?

Synonyms

Synonyms Comment Organism
beta-1,3-D-glucanase
-
 Helix pomatia
endo-beta-1,3-glucanase
-
 Helix pomatia

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Helix pomatia

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
 assay at Helix pomatia