Application | Comment | Organism |
---|---|---|
medicine | the enzyme is an immunostimulatory antigen. Glu-176, a conserved catalytic residue in GH16 endo-beta-1,3-glucanases, is essential for Rv0315 to induce immunological responses | Mycobacterium tuberculosis |
Crystallization (Comment) | Organism |
---|---|
structure of Rv0315 at 1.70 A resolution. Rv0315 is an inactive beta-1,3-glucanase of the glycoside hydrolase 16 (GH16) family. Rv0315 has a large open groove, and this particular topology cannot bind oligosaccharide chains in solution, thus explaining the lack of detectable hydrolytic activity towards its substrate | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | O07242 | - |
- |
Mycobacterium tuberculosis H37Rv | O07242 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
Rv0315 | - |
Mycobacterium tuberculosis |