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Literature summary for 3.2.1.35 extracted from

  • Kramer, M.W.; Golshani, R.; Merseburger, A.S.; Knapp, J.; Garcia, A.; Hennenlotter, J.; Duncan, R.C.; Soloway, M.S.; Jorda, M.; Kuczyk, M.A.; Stenzl, A.; Lokeshwar, V.B.
    HYAL-1 Hyaluronidase: A Potential Prognostic Indicator for Progression to Muscle Invasion and Recurrence in Bladder Cancer (2010), Eur. Urol., 57, 86-93.
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine it is assessed whether hyaluronic acid and HYAL-1 can predict progression to muscle invasion and recurrence among patients with non-muscle-invasive bladder carcinoma. In a cohort of 178 bladder carcinoma specimens HA and HYAL-1 expression is evaluated by immunohistochemistry and graded for intensity and area of staining. Association of HA and HYAL-1 staining with bladder carcinoma recurrence and muscle invasion is evaluated by univariate and multivariate models. HYAL-1 is a potential prognostic marker for predicting progression to muscle invasion and recurrence Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q12794
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Source Tissue

Source Tissue Comment Organism Textmining

Synonyms

Synonyms Comment Organism
Hyal-1
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 Homo sapiens
Hyaluronoglucosaminidase 1-type hyaluronidase
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 Homo sapiens