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Literature summary for 3.2.1.35 extracted from
- Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis (2007), Biochemistry, 46, 6911-6920.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Drosophila melanogaster Schneider 2 cells | Homo sapiens |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| hanging drop vapour diffusion method with mother liquor containing 1.5 M NaCl, 10% (v/v) ethanol, and 1/10 volume of 30% (w/v) galactose, at pH 4.6 | Homo sapiens |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 47370 | - |
calculated from sequence of cDNA | Homo sapiens |
| 50870 | - |
MALDI-TOF mass spectrometry | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q12794 | - |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Homo sapiens |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Chelating Sepharose Fast Flow column chromatography and Sephacryl S200 gel filtration | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hyaluronan + 2 H2O | - |
Homo sapiens | N-acetyl-beta-D-glucosamine + D-glucuronate + ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| endo-alpha-N-acetyl-hexosaminidase | - |
Homo sapiens |
| Hyal-1 | - |
Homo sapiens |
| hyaluronidase-1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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