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Literature summary for 3.2.1.35 extracted from
- Testicular hyaluronidase induces tubular structures of endothelial cells grown in three-dimensional collagen gel through a CD44-mediated mechanism (2002), Int. J. Cancer, 97, 601-607.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | blocking of CD44-receptors inhibits the enzyme-induced tubular structure formation of endothelial cells | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Mus musculus | CD44-mediated specific role of certain populations of testicular enzyme in the induction of angiogenesis | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Mus musculus | - |
| capillary | - |
Mus musculus | - |
| culture condition:collagen-grown cell | - |
Mus musculus | - |
| endothelial cell | cell line derived from newborn H-2kb tsA58 transgenic mice | Mus musculus | - |
| endothelium | cells form tubular structures after stimulation by angiogenic factors, e.g. the enzyme and the basic fibroblast growth factor bFGF, treatment leads to cell survival and prevents from apoptosis, respectively | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Collagen + H2O | - |
Mus musculus | ? | - |
? | |
| hyaluronan + H2O | - |
Mus musculus | ? | - |
? | |
| additional information | CD44-mediated specific role of certain populations of testicular enzyme in the induction of angiogenesis | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| hyaluronidase | - |
Mus musculus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
assay at | Mus musculus |
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Release 2023.1 (January 2023)
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