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Literature summary for 3.2.1.35 extracted from

  • Maksimenko, A.V.; Schechilina, Y.V.; Tischenko, E.G.
    Role of glycosaminoglycan microenvironment of hyaluronidase in regulation of its endoglycosidase activity (2003), Biochemistry (Moscow), 68, 1055-1062.
No PubMed abstract available
Search for more literature for 3.2.1.35

Inhibitors

Inhibitors Comment Organism Structure
dermatan sulfate
-
 Bos taurus
Dextran
-
 Bos taurus
Dextran sulfate
-
 Bos taurus
heparin 16-18 kDa Bos taurus
additional information enzyme stably covalently linked to activated glycosaminoglycans, such as heparin, dextran and dermatan sulfate, is reduced in its activity and the inhibitory effect of free heparin is increased, while chondroitin sulfate stabilizes the enzyme against heparin inhibition, effect of glycosaminoglycan fragments with different residues, at different pH values, overview Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
further purification of the commercial preparation Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
 Bos taurus
-
testicle
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hyaluronate + H2O from umbilical cord Bos taurus N-acetyl-beta-D-glucosamine + D-glucuronate + ?
-
 ?

Synonyms

Synonyms Comment Organism
HU
-
 Bos taurus
hyaluronidase
-
 Bos taurus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Bos taurus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5
-
-
 Bos taurus