Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.2.1.31 extracted from

  • Izagirre, U.; Angulo, E.; Wade, S.C.; ap Gwynn, I.; Marigomez, I.
    beta-Glucuronidase and hexosaminidase are marker enzymes for different compartments of the endo-lysosomal system in mussel digestive cells (2009), Cell Tissue Res., 335, 441-454.
    View publication on PubMed

Application

Application Comment Organism
analysis in environmental toxicology, techniques used to visualise lysosomes in order to determine their responses to pollutants are the lysosomal structural changes test and the lysosomal membrane stability test are based on the histochemical application of lysosomal marker enzymes. In mussel digestive cells, the marker enzymes used are beta-glucuronidase and hexosaminidase. beta-Glucuronidase, but not hexosaminindase, histochemistry provides an appropriate marker for the lysosomal structural changes test and that, although both lysosomal marker enzymes can be employed in the lysosomal membrane stability test, different values would be obtained depending on the marker enzyme employed Mytilus galloprovincialis
toxicology in environmental toxicology, techniques used to visualise lysosomes in order to determine their responses to pollutants are the lysosomal structural changes test and the lysosomal membrane stability test are based on the histochemical application of lysosomal marker enzymes. In mussel digestive cells, the marker enzymes used are beta-glucuronidase and hexosaminidase. beta-Glucuronidase, but not hexosaminindase, histochemistry provides an appropriate marker for the lysosomal structural changes test and that, although both lysosomal marker enzymes can be employed in the lysosomal membrane stability test, different values would be obtained depending on the marker enzyme employed Mytilus galloprovincialis

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome beta-glucuronidase is present in every compartment of the digestive cell endo-lysosomal compartment and appears to be not necessarily membrane-bound. Enzyme is released to the digestive alveolar lumen in secretory lysosomes produced by basophilic cells and endocytosed by digestive cells Mytilus galloprovincialis 5764
-

Organism

Organism UniProt Comment Textmining
Mytilus galloprovincialis B0FN51 fragment
-

Source Tissue

Source Tissue Comment Organism Textmining
digestive cell
-
Mytilus galloprovincialis
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
80 150
-
Mytilus galloprovincialis