Inhibitors | Comment | Organism | Structure |
---|---|---|---|
glucose | the enzyme is regulated by glucose-induced catabolite repression | Candida albicans | |
Mg2+ | - |
Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Saccharomyces cerevisiae | 5829 | - |
vacuole | - |
Candida albicans | 5773 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates | Saccharomyces cerevisiae | |
Mn2+ | activates | Saccharomyces cerevisiae | |
additional information | the activity is independent of divalent cations | Candida albicans |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
104000 | - |
calculated from sequence | Candida albicans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha,alpha-trehalose + H2O | Candida albicans | hydrolysis of exogenous trehalose | beta-D-glucose + alpha-D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | Saccharomyces cerevisiae | hydrolysis of intracellular trehalose in response to physiological stimuli | beta-D-glucose + alpha-D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | Candida albicans ATCC MYA-2876 | hydrolysis of exogenous trehalose | beta-D-glucose + alpha-D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | Saccharomyces cerevisiae ATCC 204508 | hydrolysis of intracellular trehalose in response to physiological stimuli | beta-D-glucose + alpha-D-glucose | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | Q5AAU5 | - |
- |
Candida albicans ATCC MYA-2876 | Q5AAU5 | - |
- |
Saccharomyces cerevisiae | P32356 | - |
- |
Saccharomyces cerevisiae ATCC 204508 | P32356 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | the enzyme is regulated by reversible phosphorylation mediated by the cAMP-PKA pathway | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha,alpha-trehalose + H2O | - |
Saccharomyces cerevisiae | beta-D-glucose + alpha-D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | - |
Candida albicans | beta-D-glucose + alpha-D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | hydrolysis of exogenous trehalose | Candida albicans | beta-D-glucose + alpha-D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | hydrolysis of intracellular trehalose in response to physiological stimuli | Saccharomyces cerevisiae | beta-D-glucose + alpha-D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | - |
Candida albicans ATCC MYA-2876 | beta-D-glucose + alpha-D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | hydrolysis of exogenous trehalose | Candida albicans ATCC MYA-2876 | beta-D-glucose + alpha-D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | - |
Saccharomyces cerevisiae ATCC 204508 | beta-D-glucose + alpha-D-glucose | - |
? | |
alpha,alpha-trehalose + H2O | hydrolysis of intracellular trehalose in response to physiological stimuli | Saccharomyces cerevisiae ATCC 204508 | beta-D-glucose + alpha-D-glucose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acid trehalase | - |
Candida albicans |
ATC1 | - |
Candida albicans |
neutral trehalase | - |
Saccharomyces cerevisiae |
NTH1 | - |
Saccharomyces cerevisiae |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
30 | - |
- |
Saccharomyces cerevisiae |
40 | - |
- |
Candida albicans |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4.5 | 5 | - |
Candida albicans |
6.8 | 7 | - |
Saccharomyces cerevisiae |