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Literature summary for 3.2.1.24 extracted from

  • Cheng, S.H.; Malcolm, S.; Pemble, S.; Winchester, B.
    Purification and comparison of the structures of human liver acidic alpha-D-mannosidases A and B (1986), Biochem. J., 233, 65-72.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.24

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
26000
-
 alpha3beta3, 3 * 62000 + 3 * 26000, SDS-PAGE, alpha-mannosidase A Homo sapiens
62000
-
 alpha3beta3, 3 * 62000 + 3 * 26000, SDS-PAGE, alpha-mannosidase A Homo sapiens
260000
-
 alpha-mannosidase B Homo sapiens
280000
-
 gel filtration, alpha-mannosidase A Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 2 isoforms, alpha-mannosidase A, B
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
to homogeneity, chromatography steps Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.5
-
 alpha-mannosidase A Homo sapiens
4.6
-
 alpha-mannosidase B Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl-alpha-D-mannopyranoside + H2O
-
 Homo sapiens 4-methylumbelliferone + alpha-D-mannopyranose
-
 ?

Subunits

Subunits Comment Organism
hexamer alpha3beta3, 3 * 62000 + 3 * 26000, SDS-PAGE, alpha-mannosidase A Homo sapiens
oligomer composed of equal amounts of 62, 58 and 26 kDa subunits Homo sapiens

Synonyms

Synonyms Comment Organism
acid alpha-mannosidase
-
 Homo sapiens