Application | Comment | Organism |
---|---|---|
medicine | inhibitors of the enzyme are used to inhibit cell proliferation and migration in a variety of different pathologies, such as viral infection, cancer, and diabetes | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | the soluble alpha subunit is retained in the endoplasmic reticulum through its interaction with the HDEL-containing beta subunit | Mus musculus | 5783 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8BHN3 | - |
- |
Mus musculus C57BL/6 | Q8BHN3 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | N-glycosylation of the enzyme | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | expression of the enzyme in all brain regions | Mus musculus | - |
cerebral cortex | higher expression | Mus musculus | - |
heart | low expression | Mus musculus | - |
kidney | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
additional information | tissue-specific expression pattern of the enzyme, overview | Mus musculus | - |
testis | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the catalytic enzyme alpha subunit, with the help of mannose 6-phosphate receptor homology domain of the beta-subunit, sequentially hydrolyzes two alpha1-3-linked glucose residues in the second step of N-linked oligosaccharide-mediated protein folding | Mus musculus | ? | - |
? | |
additional information | the catalytic enzyme alpha subunit, with the help of mannose 6-phosphate receptor homology domain of the beta-subunit, sequentially hydrolyzes two alpha1-3-linked glucose residues in the second step of N-linked oligosaccharide-mediated protein folding | Mus musculus C57BL/6 | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
heterodimer | alphabeta | Mus musculus |
More | enzyme peptide proteolysis and fragment analysis, overview | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
alpha-glucosidase II | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is continuously requirement in correct folding of cell surface proteins | Mus musculus |