Literature summary for 3.2.1.207 extracted from

Gamberucci, A.; Konta, L.; Colucci, A.; Giunti, R.; Magyar, J.E.; Mandl, J.; Banhegyi, G.; Benedetti, A.; Csala, M.
Green tea flavonols inhibit glucosidase II (2006), Biochem. Pharmacol., 72, 640-646.

Search for more literature for 3.2.1.207

Inhibitors

Inhibitors	Comment	Organism	Structure
epicatechin gallate	-	Rattus norvegicus
epigallocatechin	-	Rattus norvegicus
epigallocatechin gallate	-	Rattus norvegicus
gallocatechin	-	Rattus norvegicus
gallocatechin gallate	-	Rattus norvegicus
N-butyldeoxynojirimycin	-	Rattus norvegicus
propyl gallate	-	Rattus norvegicus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0552	-	4-methylumbelliferyl-alpha-D-glucoside	37°C	Rattus norvegicus
2.2	-	4-nitrophenyl alpha-D-glucopyranoside	37°C	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
microsome	-	Rattus norvegicus	-	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-methylumbelliferyl-alpha-D-glucoside + H2O	-	Rattus norvegicus	4-methylumbelliferone + alpha-D-glucose	-	?
4-nitrophenyl alpha-D-glucopyranoside + H2O	-	Rattus norvegicus	4-nitrophenol + alpha-D-glucopyranose	-	?

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.002027	-	gallocatechin gallate	37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside	Rattus norvegicus
0.002247	-	N-butyldeoxynojirimycin	37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside	Rattus norvegicus
0.002545	-	gallocatechin gallate	37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside	Rattus norvegicus
0.00519	-	N-butyldeoxynojirimycin	37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside	Rattus norvegicus
0.008763	-	epicatechin gallate	37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside	Rattus norvegicus
0.0131	-	epicatechin gallate	37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside	Rattus norvegicus
0.02948	-	epigallocatechin gallate	37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside	Rattus norvegicus
0.03281	-	epigallocatechin gallate	37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside	Rattus norvegicus
0.03628	-	propyl gallate	37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside	Rattus norvegicus
0.04312	-	propyl gallate	37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside	Rattus norvegicus
0.06815	-	epigallocatechin	37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside	Rattus norvegicus
0.07062	-	gallocatechin	37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside	Rattus norvegicus
0.07599	-	epigallocatechin	37°C, hydrolysis of 4-nitrophenyl alpha-D-glucopyranoside	Rattus norvegicus
0.07893	-	gallocatechin	37°C, hydrolysis of 4-methylumbelliferyl-alpha-D-glucoside	Rattus norvegicus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)