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Literature summary for 3.2.1.207 extracted from
- Specific isoforms of the resident endoplasmic reticulum protein glucosidase II associate with the CD45 protein-tyrosine phosphatase via a lectin-like interaction (2000), J. Biol. Chem., 275, 32071-32076.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | - |
Mus musculus | 5783 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 84000 | - |
SDS-PAGE, beta subunit with unknown function | Mus musculus |
| 116000 | - |
SDS-PAGE, catalytically active alpha subunit | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Mus musculus | Catalyzes the hydrolysis of the inner two alpha-1,3-linked glucose residues present in all N-linked immature oligosaccharides, associates with and glycosylates the protein CD45, possible role in CD45 regulation | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
four different isoforms generated by alternative splicing | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| BW-5147 cell | T-lymphoma cell line | Mus musculus | - |
| BW/T200- cell | CD45-negative variant of BW5147 | Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl alpha-D-glucopyranoside + H2O | - |
Mus musculus | 4-nitrophenol + D-glucose | - |
? | |
| additional information | Catalyzes the hydrolysis of the inner two alpha-1,3-linked glucose residues present in all N-linked immature oligosaccharides, associates with and glycosylates the protein CD45, possible role in CD45 regulation | Mus musculus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | alpha, beta, 1* 116000 + 1 * 84000, SDS-PAGE, catalytically active alpha subunit, beta subunit with unknown function | Mus musculus |
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Release 2023.1 (January 2023)
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