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Literature summary for 3.2.1.207 extracted from
- Quaternary and domain structure of glycoprotein processing glucosidase II (2001), Biochemistry, 40, 10717-10722.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | limited trypsin digestion of the alpha subunit resultes in a fully active fragment of 70000 Da | Rattus norvegicus |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 110000 | - |
alpha, beta, 1 * 110000 + 1 * ?, SDS-PAGE, catalytic alpha subunit and beta subunit of unknown function | Rattus norvegicus |
| 161000 | - |
analytical ultracentrifugation | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Glc2Man9GlcNAc2 + H2O | Rattus norvegicus | removal of glucose residues allows newly synthesized glycoproteins to interact with calnexin and calreticulin, that are part of the chaperone mechanism | Man9GlcNAc2 + alpha-D-glucose | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| native protein and alpha subunit | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-nitrophenyl alpha-D-glucopyranoside + H2O | - |
Rattus norvegicus | 4-nitrophenol + D-glucose | - |
? | |
| Glc2Man9GlcNAc2 + H2O | removal of glucose residues allows newly synthesized glycoproteins to interact with calnexin and calreticulin, that are part of the chaperone mechanism | Rattus norvegicus | Man9GlcNAc2 + alpha-D-glucose | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | alpha, beta, 1 * 110000 + 1 * ?, SDS-PAGE, catalytic alpha subunit and beta subunit of unknown function | Rattus norvegicus |
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Release 2023.1 (January 2023)
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