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Literature summary for 3.2.1.20 extracted from

  • Hakamata, W.; Kurihara, M.; Okuda, H.; Nishio, T.; Oku, T.
    Design and screening strategies for alpha-glucosidase inhibitors based on enzymological information (2009), Curr. Top. Med. Chem., 9, 3-12.
    View publication on PubMed

Application

Application Comment Organism
medicine target for therapy of type 2 diabetes, antitumor activites, antiviral activites Beta vulgaris
medicine target for therapy of type 2 diabetes, antitumor activites, antiviral activites Saccharomyces cerevisiae
medicine target for therapy of type 2 diabetes, antitumor activites, antiviral activites Geobacillus stearothermophilus
medicine target for therapy of type 2 diabetes, antitumor activites, antiviral activites Aspergillus niger
medicine target for therapy of type 2 diabetes, antitumor activites, antiviral activites Zea mays
medicine target for therapy of type 2 diabetes, antitumor activites, antiviral activites Apis mellifera
medicine target for therapy of type 2 diabetes, antitumor activites, antiviral activites Oryza sativa
medicine target for therapy of type 2 diabetes, antitumor activites, antiviral activites Saccharolobus solfataricus

Inhibitors

Inhibitors Comment Organism Structure
1-deoxynojirimycin
-
Apis mellifera
1-deoxynojirimycin
-
Aspergillus niger
1-deoxynojirimycin
-
Beta vulgaris
1-deoxynojirimycin
-
Geobacillus stearothermophilus
1-deoxynojirimycin
-
Oryza sativa
1-deoxynojirimycin
-
Saccharolobus solfataricus
1-deoxynojirimycin
-
Saccharomyces cerevisiae
1-deoxynojirimycin
-
Zea mays
acarbose
-
Apis mellifera
acarbose
-
Aspergillus niger
acarbose
-
Beta vulgaris
acarbose
-
Geobacillus stearothermophilus
acarbose
-
Oryza sativa
acarbose
-
Saccharolobus solfataricus
acarbose
-
Saccharomyces cerevisiae
acarbose
-
Zea mays
miglitol
-
Apis mellifera
miglitol
-
Aspergillus niger
miglitol
-
Beta vulgaris
miglitol
-
Geobacillus stearothermophilus
miglitol
-
Oryza sativa
miglitol
-
Saccharolobus solfataricus
miglitol
-
Saccharomyces cerevisiae
miglitol
-
Zea mays
voglibose
-
Apis mellifera
voglibose
-
Aspergillus niger
voglibose
-
Beta vulgaris
voglibose
-
Geobacillus stearothermophilus
voglibose
-
Oryza sativa
voglibose
-
Saccharolobus solfataricus
voglibose
-
Saccharomyces cerevisiae
voglibose
-
Zea mays

Organism

Organism UniProt Comment Textmining
Apis mellifera
-
-
-
Aspergillus niger
-
-
-
Beta vulgaris
-
-
-
Geobacillus stearothermophilus
-
-
-
Oryza sativa
-
-
-
Saccharolobus solfataricus P0CD66
-
-
Saccharomyces cerevisiae
-
-
-
Zea mays
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl alpha-D-glucopyranoside + H2O
-
Beta vulgaris 4-nitrophenol + D-glucose
-
?
4-nitrophenyl alpha-D-glucopyranoside + H2O
-
Saccharomyces cerevisiae 4-nitrophenol + D-glucose
-
?
4-nitrophenyl alpha-D-glucopyranoside + H2O
-
Geobacillus stearothermophilus 4-nitrophenol + D-glucose
-
?
4-nitrophenyl alpha-D-glucopyranoside + H2O
-
Aspergillus niger 4-nitrophenol + D-glucose
-
?
4-nitrophenyl alpha-D-glucopyranoside + H2O
-
Zea mays 4-nitrophenol + D-glucose
-
?
4-nitrophenyl alpha-D-glucopyranoside + H2O
-
Apis mellifera 4-nitrophenol + D-glucose
-
?
4-nitrophenyl alpha-D-glucopyranoside + H2O
-
Oryza sativa 4-nitrophenol + D-glucose
-
?

Synonyms

Synonyms Comment Organism
alpha-glucosidase
-
Beta vulgaris
alpha-glucosidase
-
Saccharomyces cerevisiae
alpha-glucosidase
-
Geobacillus stearothermophilus
alpha-glucosidase
-
Aspergillus niger
alpha-glucosidase
-
Zea mays
alpha-glucosidase
-
Apis mellifera
alpha-glucosidase
-
Oryza sativa
alpha-glucosidase
-
Saccharolobus solfataricus