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Literature summary for 3.2.1.18 extracted from

  • Piagnerelli, M.; Boudjeltia, K.Z.; Rapotec, A.; Richard, T.; Brohee, D.; Babar, S.; Bouckaert, V.; Simon, A.C.; Toko, J.P.; Walravens, T.; Vincent, J.L.; Vanhaeverbeek, M.
    Neuraminidase alters red blood cells in sepsis (2009), Crit. Care Med., 37, 1244-1250.
    View publication on PubMed

Application

Application Comment Organism
medicine neuraminidase activity is significantly higher in septic patients compared with nonseptic patients and healthy volunteers. Desialylation by increased neuramindase activity may contribute to the alternations in red blood cell rheology Homo sapiens
medicine treatment of red blood cells with enzyme modifies their shape in a dose-dependent fashion. Cells become more spherical, and alterations remain for at least ten hours. Changes are similar to changes during sepsis Clostridium perfringens

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Clostridium perfringens
-
-
-
Homo sapiens
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acute ill patients with and without sepsis
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Source Tissue

Source Tissue Comment Organism Textmining
blood
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Homo sapiens
-