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Literature summary for 3.2.1.176 extracted from

  • Kont, R.; Kari, J.; Borch, K.; Westh, P.; Vaeljamaee, P.
    Inter-domain synergism is required for efficient feeding of cellulose chain into active site of cellobiohydrolase Cel7A (2016), J. Biol. Chem., 291, 26013-26023 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Aspergillus oryzae Trichoderma reesei

Protein Variants

Protein Variants Comment Organism
W38A the mutant shows an increased Km value for Avicel compared to the wild type enzyme Trichoderma reesei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cellulose + H2O Trichoderma reesei
-
cellobiose + ?
-
?
cellulose + H2O Trichoderma reesei QM 9414
-
cellobiose + ?
-
?

Organism

Organism UniProt Comment Textmining
Trichoderma reesei
-
-
-
Trichoderma reesei QM 9414
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
amorphous cellulose + H2O
-
Trichoderma reesei ?
-
?
amorphous cellulose + H2O
-
Trichoderma reesei QM 9414 ?
-
?
avicel + H2O
-
Trichoderma reesei ?
-
?
avicel + H2O
-
Trichoderma reesei QM 9414 ?
-
?
bacterial cellulose + H2O
-
Trichoderma reesei ?
-
?
bacterial cellulose + H2O
-
Trichoderma reesei QM 9414 ?
-
?
cellulose + H2O
-
Trichoderma reesei cellobiose + ?
-
?
cellulose + H2O
-
Trichoderma reesei QM 9414 cellobiose + ?
-
?

Synonyms

Synonyms Comment Organism
Cel7A
-
Trichoderma reesei
cellobiohydrolase
-
Trichoderma reesei