Application | Comment | Organism |
---|---|---|
synthesis | the enzyme can be used for biotransformation of glycone baicalin to more pharmacologically active aglycone baicalein in extracts from Scutellaria baicalensis Georgi plant roots. Development of a chemically defined medium-based baicalein bioproduction process with a comparable yield compared to complex medium-based ones, overview | Helix pomatia |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
baicalin + H2O | Helix pomatia | - |
baicalein + D-glucuronate | - |
? |
Organic Solvent | Comment | Organism |
---|---|---|
dimethyl formamide | enzyme HP-GUS retains its catalytic activity in presence of 5% DMF, which is required in the biotransformation assay due to a low solubility and insolubility problem of baicalin and baicalein at reaction pH 4.5, respectively | Helix pomatia |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Helix pomatia | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
baicalin + H2O | - |
Helix pomatia | baicalein + D-glucuronate | - |
? | |
baicalin + H2O | baicalein 7-O-beta-D-glucuronide | Helix pomatia | baicalein + D-glucuronate | - |
? | |
additional information | development of a chemically defined medium-based baicalein bioproduction process with a comparable yield compared to complex medium-based ones, detailed overview | Helix pomatia | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta-glucuronidase | - |
Helix pomatia |
GUS | - |
Helix pomatia |
HP-GUS | - |
Helix pomatia |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Helix pomatia |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4.5 | - |
- |
Helix pomatia |