Inhibitors | Comment | Organism | Structure |
---|---|---|---|
heparin | commercial heparin is a powerful inhibitor of heparanase action toward antithrombin-binding oligosaccharides | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y251 | recombinant | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
heparin + H2O | heparanase cleaves macromolecular heparin at multiple sites. Heparanase primarily cleaves target structures distinct from the antithrombin-binding sequence | Homo sapiens | ? | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00002 | - |
heparanase action toward antithrombin-binding oligosaccharides | Homo sapiens | heparin |