Crystallization (Comment) | Organism |
---|---|
purified recombinant enzyme in complex with inhibitor 1, hanging drop vapor diffusion, 0.0002 ml of protein solution containing 0.44 mM AMCase, 0.52 mM inhibitor 1, 25 mM Tris-HCl, pH 8.0, and 50 mM NaCl, is mixed with 0.0002 ml of reservoir solution containing 20% PEG MME 5000, 100 mM bis-Tris, equilibration over 0.2 ml of reservoir solution, pH 6.5, 18°C, 2 weeks, X-ray diffraction structure determination and analysis, modeling | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-(piperazin-1-yl)pyridine-3-carboxamide | - |
Homo sapiens | |
2-methyl-3-[[4-(pyridin-2-yl)piperazin-1-yl]methyl]-1H-indole | - |
Homo sapiens | |
4-(4-chlorophenyl)piperazine-1-carboximidamide | - |
Homo sapiens | |
5-[4-[2-(4-bromophenoxy)ethyl]piperazin-1-yl]-1H-1,2,4-triazol-3-amine | - |
Homo sapiens | |
N-ethyl-2-(4-methylpiperazin-1-yl)pyridine-3-carboxamide | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | recombinant enzyme | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl-beta-D-N,N'-diacetylchitobioside + H2O | - |
Homo sapiens | 4-methylumbelliferone + N,N'-diacetylchitobiose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AMCase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5 | - |
assay at | Homo sapiens |