Literature summary for 3.2.1.130 extracted from

Dedola, S.; Izumi, M.; Makimura, Y.; Seko, A.; Kanamori, A.; Takeda, Y.; Ito, Y.; Kajihara, Y.
Direct assay for endo-alpha-mannosidase substrate preference on correctly folded and misfolded model glycoproteins (2016), Carbohydr. Res., 434, 94-98 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q5SRI9	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GlcMan9GlcNAc2-[protein] + H2O	the enzyme removes Glc-alpha-(1->3)-Man unit from G1M9-native and -misfolded-crambins. The enzyme does not have specific preference for correctly folded or misfolded protein structure	Homo sapiens	Man8GlcNAc2-[protein] (isomer 8A1,2,3B1,2) + alpha-D-glucosyl-(1->3)-alpha-D-mannopyranose	-	?

Synonyms

Synonyms	Comment	Organism
Golgi endo-a-mannosidase	-	Homo sapiens

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Release 2023.1 (January 2023)