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Literature summary for 3.2.1.129 extracted from

  • Li, C.; Zhang, Y.X.; Yang, C.; Hao, F.; Chen, S.S.; Hao, Q.; Lu, T.; Qu, T.Y.; Zhao, L.R.; Duan, W.M.
    Intraventricular administration of endoneuraminidase-N facilitates ectopic migration of subventricular zone-derived neural progenitor cells into 6-OHDA lesioned striatum of mice (2016), Exp. Neurol., 277, 139-149 .
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
polysialylated neural cell adhesion molecule + H2O Mus musculus
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 ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
striatum
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
polysialylated neural cell adhesion molecule + H2O
-
 Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
endo-N
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 Mus musculus
endoneuraminidase-N
-
 Mus musculus

General Information

General Information Comment Organism
physiological function the enzyme inhibits the migration and enhances the differentiation of neural progenitor cells. Interruption of neuroblast chain pathway with the enzyme facilitates ectopic migration of subventricular zone-derived neural progenitor cells into the lesioned striatum, and migrated neural progenitor cells can differentiate into neurons and astrocytes Mus musculus