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Literature summary for 3.2.1.129 extracted from

  • Hsu, H.J.; Palka-Hamblin, H.; Bhide, G.P.; Myung, J.H.; Cheong, M.; Colley, K.J.; Hong, S.
    Noncatalytic endosialidase enables surface capture of small-cell lung cancer cells utilizing strong dendrimer-mediated enzyme-glycoprotein interactions (2018), Anal. Chem., 90, 3670-3675 .
    View publication on PubMedView publication on EuropePMC
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Application

Application Comment Organism
medicine a noncatalytic enzyme is used for detecting small-cell lung cancer circulating tumor cells Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-2,8-linked polysialic acid + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
COS-1 cell
-
 Homo sapiens
-
HL-60 cell
-
 Homo sapiens
-
MDA-MB-361 cell
-
 Homo sapiens
-
NCI-H69 cell
-
 Homo sapiens
-
small cell lung cancer cell
-
 Homo sapiens
-
SW-2 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-2,8-linked polysialic acid + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
EndoN Trap noncatalytic endosialidase Homo sapiens
EndoNt noncatalytic endosialidase Homo sapiens
endosialidase
-
 Homo sapiens