Glycyrrhizin beta-D-glucuronidase of Eubacterium sp. from human intestinal flora

Akao, Ta.; Akao, Te.; Kobashi, K.; Chem. Pharm. Bull. 35, 705-710 (1987)

Data extracted from this reference:

Reaction

Commentary

Organism

Reaction ID

glycyrrhizin + H2O = beta-D-glucuronosyl-(1->2)-D-glucuronate + glycyrrhetinate

the glycyrrhizin-hydrolysing enzyme is separated from the general beta-glucorinidase EC 3.2.1.31

Eubacterium sp.

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

Substrate Product ID

glycyrrhizinic acid + H2O

-

646710

Eubacterium sp.

glycyrrhetinic acid + D-glucuronyl beta-1,2-D-glucuronic acid

-

646710

Eubacterium sp.

?

Substrates

Commentary Substrates

Literature (Substrates)

Organism

Products

Commentary (Products)

Literature (Products)

Organism (Products)

Reversibility

ID

glycyrrhizinic acid + H2O

-

646710

Eubacterium sp.

glycyrrhetinic acid + D-glucuronyl beta-1,2-D-glucuronic acid

-

646710

Eubacterium sp.

?

No.

1st author

Pub Med

title

organims

journal

volume

pages

year

Activating Compound

Application

Cloned(Commentary)

Crystallization (Commentary)

Engineering

General Stability

Inhibitors

KM Value [mM]

Localization

Metals/Ions

Molecular Weight [Da]

Natural Substrates/ Products (Substrates)

Organic Solvent Stability

Organism

Oxidation Stability

Posttranslational Modification

Purification (Commentary)

Reaction

Renatured (Commentary)

Source Tissue

Specific Activity [micromol/min/mg]

Storage Stability

Substrates and Products (Substrate)

Subunits

Synonyms

Temperature Optimum [°C]

Temperature Range [°C]

Temperature Stability [°C]

Turnover Number [1/s]

pH Optimum

pH Range

pH Stability

Cofactor

Ki Value [mM]

pI Value

IC50 Value

Activating Compound (protein specific)

Application (protein specific)

Cloned(Commentary) (protein specific)

Cofactor (protein specific)

Crystallization (Commentary) (protein specific)

Engineering (protein specific)

General Stability (protein specific)

IC50 Value (protein specific)

Inhibitors (protein specific)

Ki Value [mM] (protein specific)

KM Value [mM] (protein specific)

Localization (protein specific)

Metals/Ions (protein specific)

Molecular Weight [Da] (protein specific)

Natural Substrates/ Products (Substrates) (protein specific)

Organic Solvent Stability (protein specific)

Oxidation Stability (protein specific)

Posttranslational Modification (protein specific)

Purification (Commentary) (protein specific)

Renatured (Commentary) (protein specific)

Source Tissue (protein specific)

Specific Activity [micromol/min/mg] (protein specific)

Storage Stability (protein specific)

Substrates and Products (Substrate) (protein specific)

Subunits (protein specific)

Temperature Optimum [°C] (protein specific)

Temperature Range [°C] (protein specific)

Temperature Stability [°C] (protein specific)

Turnover Number [1/s] (protein specific)

pH Optimum (protein specific)

pH Range (protein specific)

pH Stability (protein specific)

pI Value (protein specific)

Expression

General Information

General Information (protein specific)

Expression (protein specific)

KCat/KM [mM/s]

KCat/KM [mM/s] (protein specific)

681484

Lu

Biocatalytic properties of a n ...

Anas platyrhynchos

J. Mol. Catal. B

43

148-152

2006

1

-

-

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4

1

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1

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1

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1

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1

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4

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1

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1

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1

1

1

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-

286343

Akao

Distribution of enzymes involv ...

Rattus norvegicus

Biol. Pharm. Bull.

21

1036-1044

1998

-

-

-

-

-

-

-

-

-

-

-

1

-

1

-

-

-

1

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8

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2

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646711

Akao

Intestinal bacterial hydrolysi ...

Eubacterium sp.

J. Pharm. Pharmacol.

46

135-137

1994

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646709

Sasaki

-

Substrate specificity of glycy ...

Aspergillus niger

Agric. Biol. Chem.

52

207-210

1988

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9

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646710

Akao

Glycyrrhizin beta-D-glucuronid ...

Eubacterium sp.

Chem. Pharm. Bull.

35

705-710

1987

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646708

Muro

-

Purification and some properti ...

Aspergillus niger, Aspergillus niger GRM 3

Agric. Biol. Chem.

50

687-692

1986

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