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Literature summary for 3.2.1.124 extracted from
- Kdo hydrolase is required for Francisella tularensis virulence and evasion of TLR2-mediated innate immunity (2013), mBio, 4, 00638-00612.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli DH5alpha cells | Francisella tularensis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Francisella tularensis | - |
- |
- |
| Francisella tularensis LVS | - |
- |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 3-deoxy-D-manno-octulosonic acid hydrolase | - |
Francisella tularensis |
| KdhAB | - |
Francisella tularensis |
| Kdo hydrolase | - |
Francisella tularensis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | immunization of mice with the kdhAB-deficient mutant provides significant protection against fully virulent Francisella tularensis type A strain Schu S4 | Francisella tularensis |
| physiological function | the enzyme is involved in the virulence of Francisella tularensis strain LVS | Francisella tularensis |
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Release 2023.1 (January 2023)
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