Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | effect of tunicamycin and castanospermine on the production of the 3 forms of alpha-mannosidase III | Spodoptera frugiperda |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | at least 3 forms of alpha-mannosidase III, the smallest form accumulates in the extracellular fraction | Spodoptera frugiperda | - |
- |
Golgi apparatus | alpha-mannosidase III | Spodoptera frugiperda | 5794 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | alpha-mannosidase III, cobalt-dependent | Spodoptera frugiperda |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Spodoptera frugiperda | study of biosynthesis and processing of alpha-mannosidase III | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Spodoptera frugiperda | - |
at least 3 different forms of ManIII | - |
Spodoptera frugiperda | - |
Sf-9, alpha-mannosidase III | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | alpha-mannosidase III is initially synthesized as a high-mannose glycoprotein precursor, its N-glycans are trimmed as it is transported to the Golgi apparatus, N-glycosylation is required for the production of active enzyme | Spodoptera frugiperda |
additional information | study of biosynthesis and processing of alpha-mannosidase III | Spodoptera frugiperda |
proteolytic modification | a subpopulation of Golgi alpha-mannosidase III appears to be proteolytically cleaved and is secreted in enzymically active form | Spodoptera frugiperda |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | alpha-mannosidase III hydrolyzes (Man)5-9(GlcNAc)2, not: GlcNAc(Man)5(GlcNAc)2 | Spodoptera frugiperda | ? | - |
? | |
additional information | study of biosynthesis and processing of alpha-mannosidase III | Spodoptera frugiperda | ? | - |
? | |
pyridylaminated (Man)5(GlcNAc)2 + H2O | alpha-mannosidase III | Spodoptera frugiperda | pyridylaminated (Man)3(GlcNAc)2 + alpha-D-mannose | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
neutral pH-optimum | Spodoptera frugiperda |