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Literature summary for 3.2.1.11 extracted from

  • Jiao, Y.L.; Wang, S.J.; Lv, M.S.; Jiao, B.H.; Li, W.J.; Fang, Y.W.; Liu, S.
    Characterization of a marine-derived dextranase and its application to the prevention of dental caries (2014), J. Ind. Microbiol. Biotechnol., 41, 17-26.
    View publication on PubMed

Application

Application Comment Organism
medicine isoform Dex410 effectively inhibits the Streptococcus mutans bio­film growth in coverage, biomass, and water-soluble glucan by more than 80, 90, and 95%, respectively. For short-term use of 1.5 months in animal experiment, both Dex410 and the commercial mouth­wash Biotene have a significant inhibitory effect on caries, while for 3 months use, only Dex410 shows significant inhibitory effect on dental caries Arthrobacter sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
64000
-
x * 64000, SDS-PAGE Arthrobacter sp.

Organism

Organism UniProt Comment Textmining
Arthrobacter sp.
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
11.9
-
pH 5.5, 45°C Arthrobacter sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dextran T2000 + H2O
-
Arthrobacter sp. isomaltotriose + isomaltotetraose + isomaltopentaose main end-products ?

Subunits

Subunits Comment Organism
? x * 64000, SDS-PAGE Arthrobacter sp.

Synonyms

Synonyms Comment Organism
Dex410
-
Arthrobacter sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
45
-
-
Arthrobacter sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5
-
-
Arthrobacter sp.