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Literature summary for 3.2.1.108 extracted from

  • Naz, S.; Siddiqi, R.; Dew, T.P.; Williamson, G.
    Epigallocatechin-3-gallate inhibits lactase but is alleviated by salivary proline-rich proteins (2011), J. Agric. Food Chem., 59, 2734-2738.
    View publication on PubMed
Search for more literature for 3.2.1.108

Inhibitors

Inhibitors Comment Organism Structure
epigallocatechin-3-gallate inhibition by epigallocatechin-3-gallate of lactase is alleviated about 1.7fold by proline-rich proteins Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
small intestine
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lactose + H2O
-
 Rattus norvegicus D-galactose + D-glucose
-
 ?

Synonyms

Synonyms Comment Organism
lactase phlorizin hydrolase
-
 Rattus norvegicus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.074
-
 in the absence of proline-rich protein fraction, in 1.5 mM sodium phosphate buffer (pH 6.8), at 37°C Rattus norvegicus epigallocatechin-3-gallate
0.126
-
 in the presence of proline-rich protein fraction, in 1.5 mM sodium phosphate buffer (pH 6.8), at 37°C Rattus norvegicus epigallocatechin-3-gallate