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Literature summary for 3.2.1.106 extracted from

  • Simons, J.F.; Ebersold, M.; Helenius, A.
    Cell wall 1,6-beta-glucan synthesis in Saccharomyces cerevisiae depends on ER glucosidases I and II, and the molecular chaperone BiP/Kar2p (1998), EMBO J., 17, 396-405.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.2.1.106

Cloned(Commentary)

Cloned (Comment) Organism
CWH41 gene, encodes yeast glucosidase I Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
1-deoxynojirimycin
-
 Saccharomyces cerevisiae
castanospermine
-
 Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum
-
 Saccharomyces cerevisiae 5783
-
membrane type-II transmembrane protein Saccharomyces cerevisiae 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Glc3Man9GlcNAc2 + H2O Saccharomyces cerevisiae hydrolyses specifically terminal alpha1,2-linked glucose residue ?
-
 ?
Glc3Man9GlcNAc2 + H2O Saccharomyces cerevisiae specific involvement in the N-linked oligosaccharide-processing pathway ?
-
 ?
additional information Saccharomyces cerevisiae involved in first step of processing of oligosaccharides after transfer from dolichyl diphosphate to proteins ?
-
 ?
additional information Saccharomyces cerevisiae indirect role in cell wall beta1,6-glucan biosynthesis and/or in beta1,6-glucan insertion into the cell wall ?
-
 ?
additional information Saccharomyces cerevisiae cell wall 1,6-beta-glucan synthesis depends on endoplasmic reticulum glucosidase I and II, and the molecular chaperone BiP/Kar2p in a synergistic manner ?
-
 ?
additional information Saccharomyces cerevisiae involved in the formation of high mannose and complex glycoproteins ?
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Glc3Man9GlcNAc2 + H2O hydrolyses specifically terminal alpha1,2-linked glucose residue Saccharomyces cerevisiae D-glucose + Glc2Man9GlcNAc2
-
 ?
Glc3Man9GlcNAc2 + H2O hydrolyses specifically terminal alpha1,2-linked glucose residue Saccharomyces cerevisiae ?
-
 ?
Glc3Man9GlcNAc2 + H2O specific involvement in the N-linked oligosaccharide-processing pathway Saccharomyces cerevisiae ?
-
 ?
additional information involved in first step of processing of oligosaccharides after transfer from dolichyl diphosphate to proteins Saccharomyces cerevisiae ?
-
 ?
additional information indirect role in cell wall beta1,6-glucan biosynthesis and/or in beta1,6-glucan insertion into the cell wall Saccharomyces cerevisiae ?
-
 ?
additional information cell wall 1,6-beta-glucan synthesis depends on endoplasmic reticulum glucosidase I and II, and the molecular chaperone BiP/Kar2p in a synergistic manner Saccharomyces cerevisiae ?
-
 ?
additional information involved in the formation of high mannose and complex glycoproteins Saccharomyces cerevisiae ?
-
 ?

Synonyms

Synonyms Comment Organism
CWH41
-
 Saccharomyces cerevisiae
Cwh41p CWH41 gene encodes glucosidase I Saccharomyces cerevisiae