Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,2,3-tri-O-galloyl-beta-D-glucose | about 20% inhibition at 1 mM | Rattus norvegicus | |
1-O-Galloyl-beta-D-glucose | about 15% inhibition at 1 mM, 34.4% inhibition at 5 mM | Rattus norvegicus | |
1-O-methyl-2,3-di-O-galloyl-beta-D-glucose | about 10% inhibition at 1 mM | Rattus norvegicus | |
casuarictin | ellagtannin, from flower buds of Syzygium aromaticum, about 16% inhibition at 1 mM | Rattus norvegicus | |
eugeniin | ellagtannin, from flower buds of Syzygium aromaticum, about 18% inhibition at 1 mM | Rattus norvegicus | |
gallic acid | 8% inhibition at 5mM | Rattus norvegicus | |
additional information | structure-activity relationship study of inhibitors, inhibitory effect of the inhibitors on the different enzyme activities, such as maltase, sucrase and isomaltase activity, overview, an increasing number of galloyl units in the molecule leads to an increase in inhibitory potency | Rattus norvegicus | |
penta-O-galloyl-beta-D-glucose | about 40% inhibition at 1-5 mM | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Rattus norvegicus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
enzyme complex of sucrase and isomaltase integrated into the intestinal alpha-glucosidase function with the complex of maltase-glucoamylase | - |
Purification (Comment) | Organism |
---|---|
purification of the enzyme complex from rat intestinal acetone powder, by solubilization with Triton X-100, gel filtration, dialysis, ion exchange chromatography, and preparative PAGE | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl beta-D-glucoside + H2O | - |
Rattus norvegicus | 4-methylumbelliferol + beta-D-glucose | - |
? | |
sucrose + H2O | - |
Rattus norvegicus | D-fructose + D-glucose | - |
? |
Synonyms | Comment | Organism |
---|---|---|
S-I | - |
Rattus norvegicus |
sucrase-isomaltase | - |
Rattus norvegicus |