Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-Amino-2-ethyl-1,3-propanediol | 80% inhibition of isomaltase activity by 50 mM | Homo sapiens | |
2-amino-2-methyl-1,3-propanediol | almost complete inhibition of isomaltase activity by 50 mM | Homo sapiens | |
diethanolamine | about 80% inhibition of isomaltase activity by 50 mM | Homo sapiens | |
Monoethanolamine | about 70% inhibition of isomaltase activity by 50 mM | Homo sapiens | |
triethanolamine | about 80% inhibition of isomaltase activity by 50 mM | Homo sapiens | |
Tris | complete inhibition of isomaltase activity by 50 mM | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
brush border | of the small intestinal absorptive cells of the villus and the crypts | Homo sapiens | 5903 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
130000 | - |
SDS-PAGE | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
oligosaccharide + H2O | Homo sapiens | role in absorption of sucrose, isomaltose, maltose | monosaccharide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
proteolytic modification | pro-sucrase-isomaltase precursor, complex glycosylated sucrase-isomaltase precursor, high-mannose sucrase-isomaltase precursor | Homo sapiens |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
alpha-D-glucopyranosyl-(1-4)-[alpha-D-glucopyranosyl-(1-6)]-alpha-D-glucopyranosyl-(1-4)-alpha-D-glucopyranosyl-(1-4)-alpha-D-glucopyranose + H2O = alpha-D-glucopyranosyl-(1-4)-alpha-D-glucopyranosyl-(1-4)-alpha-D-glucopyranosyl-(1-4)-alpha-D-glucopyranose + D-glucose | enzyme from intestinal mucosa also catalyzes the reaction of sucrase alpha-glucosidase, EC 3.2.1.48 | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
small intestine | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
2.3 | - |
purified enzyme, isomaltose as substrate | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
isomaltosaccharides + H2O | n = 2, isomaltose | Homo sapiens | D-glucose | - |
? | |
isomaltose + H2O | - |
Homo sapiens | 2 D-glucose | - |
? | |
oligosaccharide + H2O | role in absorption of sucrose, isomaltose, maltose | Homo sapiens | monosaccharide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
isomaltase | - |
Homo sapiens |
sucrase-isomaltase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
- |
Homo sapiens |