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Literature summary for 3.13.2.1 extracted from

  • Knudsen, R.C.; Yall, I.
    Partial purification and characterization of S-adenosylhomocysteine hydrolase isolated from Saccharomyces cerevisiae (1972), J. Bacteriol., 112, 569-575.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.13.2.1

Activating Compound

Activating Compound Comment Organism Structure
adenosine deaminase
-
 Saccharomyces cerevisiae

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Saccharomyces cerevisiae

General Stability

General Stability Organism
stable to lyophilization Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
adenine
-
 Saccharomyces cerevisiae
Adenosine diphosphate
-
 Saccharomyces cerevisiae
adenosine-2'-monophosphate
-
 Saccharomyces cerevisiae
adenosine-3',5'-cyclic monophosphate
-
 Saccharomyces cerevisiae
Adenosine-3'-monophosphate
-
 Saccharomyces cerevisiae
adenosine-5'-monophosphate
-
 Saccharomyces cerevisiae
ATP
-
 Saccharomyces cerevisiae
cysteine
-
 Saccharomyces cerevisiae
deoxyadenosine
-
 Saccharomyces cerevisiae
L-homocysteine
-
 Saccharomyces cerevisiae
uridine
-
 Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-adenosyl-L-homocysteine + H2O Saccharomyces cerevisiae
-
 adenosine + L-homocysteine
-
 r

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Purification (Commentary)

Purification (Comment) Organism
25.1fold, partial Saccharomyces cerevisiae

Reaction

Reaction Comment Organism Reaction ID
S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine reaction equilibrium is in vitro strongly in direction of synthesis of S-adenosyl-L-homocysteine Saccharomyces cerevisiae
a

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.503
-
-
 Saccharomyces cerevisiae

Storage Stability

Storage Stability Organism
frozen, stable for several months Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DL-homocysteine + 3-deazaadenosine
-
 Saccharomyces cerevisiae ?
-
 r
DL-homocysteine thiolactone
-
 Saccharomyces cerevisiae ?
-
 r
S-adenosyl-L-homocysteine + H2O
-
 Saccharomyces cerevisiae adenosine + L-homocysteine
-
 r

pH Stability

pH Stability pH Stability Maximum Comment Organism
5
-
 labile Saccharomyces cerevisiae