Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bisulfite | reversible | Rattus norvegicus | |
DL-homocysteine | competitive | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00105 | - |
adenosine | - |
Rattus norvegicus | |
0.0152 | - |
S-adenosyl-L-homocysteine | - |
Rattus norvegicus | |
0.1548 | - |
DL-homocysteine | - |
Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
47000 | - |
4 * 47000, SDS-PAGE, probably homomeric | Rattus norvegicus |
188000 | - |
gel filtration | Rattus norvegicus |
190000 | - |
sedimentation equilibrium | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-homocysteine + H2O | Rattus norvegicus | - |
adenosine + L-homocysteine | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Wistar rats | - |
Purification (Comment) | Organism |
---|---|
to homogeneity | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.77 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
DL-homocysteine + 3-deazaadenosine | - |
Rattus norvegicus | ? | - |
r | |
DL-homocysteine + adenosine | - |
Rattus norvegicus | S-adenosyl-DL-homocysteine | - |
r | |
S-adenosyl-L-homocysteine + H2O | - |
Rattus norvegicus | adenosine + L-homocysteine | - |
r |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 47000, SDS-PAGE, probably homomeric | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.4 | 7.2 | hydrolysis of S-adenosyl-L-homocysteine | Rattus norvegicus |
7.8 | - |
synthesis of S-adenosyl-L-homocysteine | Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Rattus norvegicus |