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Literature summary for 3.13.1.1 extracted from

  • Zolghadr, B.; Gasselhuber, B.; Windwarder, M.; Pabst, M.; Kracher, D.; Kerndl, M.; Zayni, S.; Hofinger-Horvath, A.; Ludwig, R.; Haltrich, D.; Oostenbrink, C.; Obinger, C.; Kosma, P.; Messner, P.; Schäffer, C.
    UDP-sulfoquinovose formation by Sulfolobus acidocaldarius (2015), Extremophiles, 19, 451-467.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
E147A strongly impaired conversion of UDP-D-glucose to UDP-D-glucose-5,6-ene Sulfolobus acidocaldarius
H95A inactive mutant enzyme Sulfolobus acidocaldarius
K186A impaired conversion of UDP-D-glucose to UDP-D-glucose-5,6-ene Sulfolobus acidocaldarius
M145A inactive mutant enzyme Sulfolobus acidocaldarius
R101A inactive mutant enzyme Sulfolobus acidocaldarius
T144A mutant enzyme with fully retained activity, conversion of UDP-D-glucose to UDP-D-glucose-5,6-ene Sulfolobus acidocaldarius
Y148A strongly impaired conversion of UDP-D-glucose to UDP-D-glucose-5,6-ene Sulfolobus acidocaldarius
Y182A impaired conversion of UDP-D-glucose to UDP-D-glucose-5,6-ene Sulfolobus acidocaldarius

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-alpha-D-glucose + sulfite Sulfolobus acidocaldarius the activated form of sulfoquinovose is required for its incorporation into glycoconjugates UDP-alpha-D-sulfoquinovopyranose + H2O
-
?
UDP-alpha-D-glucose + sulfite Sulfolobus acidocaldarius DSM 639 the activated form of sulfoquinovose is required for its incorporation into glycoconjugates UDP-alpha-D-sulfoquinovopyranose + H2O
-
?

Organism

Organism UniProt Comment Textmining
Sulfolobus acidocaldarius Q4JBJ3
-
-
Sulfolobus acidocaldarius DSM 639 Q4JBJ3
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucose + sulfite the activated form of sulfoquinovose is required for its incorporation into glycoconjugates Sulfolobus acidocaldarius UDP-alpha-D-sulfoquinovopyranose + H2O
-
?
UDP-alpha-D-glucose + sulfite final hydride transfer occurs to C-4 rather than C-6 of the enone form of UDP-4-dehydro-D-glucose, leaving this carbon accessible for the subsequent addition of sulfite Sulfolobus acidocaldarius UDP-alpha-D-sulfoquinovopyranose + H2O
-
?
UDP-alpha-D-glucose + sulfite the activated form of sulfoquinovose is required for its incorporation into glycoconjugates Sulfolobus acidocaldarius DSM 639 UDP-alpha-D-sulfoquinovopyranose + H2O
-
?
UDP-alpha-D-glucose + sulfite final hydride transfer occurs to C-4 rather than C-6 of the enone form of UDP-4-dehydro-D-glucose, leaving this carbon accessible for the subsequent addition of sulfite Sulfolobus acidocaldarius DSM 639 UDP-alpha-D-sulfoquinovopyranose + H2O
-
?

Synonyms

Synonyms Comment Organism
Agl3
-
Sulfolobus acidocaldarius

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
70
-
-
Sulfolobus acidocaldarius

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
Sulfolobus acidocaldarius