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Literature summary for 3.11.1.1 extracted from

  • Baker, A.S.; Ciocci, M.J.; Metcalf, W.W.; Kim, J.; Babbitt, P.C.; Wanner, B.L.; Martin, B.M.; Dunaway-Mariano, D.
    Insight into the mechanism of catalysis by the P-C cleaving enzyme phosphonoacetaldehyde hydrolase derived from gene sequence analysis and mutagenesis (1998), Biochemistry, 37, 9305-9315.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
high-level-expression in E coli Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism UniProt Comment Textmining
Bacillus cereus
-
-
-
Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Reaction

Reaction Comment Organism Reaction ID
phosphonoacetaldehyde + H2O = acetaldehyde + phosphate mechanism involves Schiff base formation with Lys53 followed by phosphoryl transfer to Asp11 and at last hydrolysis at the imine and acyl phosphate phosphorus Salmonella enterica subsp. enterica serovar Typhimurium
phosphonoacetaldehyde + H2O = acetaldehyde + phosphate mechanism involves Schiff base formation with Lys53 followed by phosphoryl transfer to Asp12 and at last hydrolysis at the imine and acyl phosphate phosphorus Bacillus cereus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphonoacetylaldehyde + H2O
-
Salmonella enterica subsp. enterica serovar Typhimurium acetaldehyde + phosphate
-
?
phosphonoacetylaldehyde + H2O
-
Bacillus cereus acetaldehyde + phosphate
-
?