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Literature summary for 3.1.8.1 extracted from
- Differential effects of some antibiotics on paraoxonase enzyme activity on human hepatoma cells (HepG2) in vitro (2010), J. Enzyme Inhib. Med. Chem., 25, 715-719.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ciprofloxacin | IC50 of 0.02175 mg/ml 6 h after the drug application | Homo sapiens |  |
| clindamiycin phosphate | IC50 of 0.2395 mg/ml 6 h after the drug application | Homo sapiens | |
| rifamycin SV | IC50 of 0.00265 mg/ml 6 h after the drug application | Homo sapiens | |
| sodium ampicillin | IC50 of 0.03266 mg/ml 6 h after the drug application | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Hep-G2 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| paraoxon + H2O | - |
Homo sapiens | 4-nitrophenol + diethyl phosphate | - |
? | |
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