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Literature summary for 3.1.8.1 extracted from

  • Jackson, C.J.; Liu, J.W.; Coote, M.L.; Ollis, D.L.
    The effects of substrate orientation on the mechanism of a phosphotriesterase (2005), Org. Biomol. Chem., 3, 4343-4350.
    View publication on PubMed
Search for more literature for 3.1.8.1

Application

Application Comment Organism
degradation the enzyme is used for the detoxification of organophosphate pesticides and realted chemical warfare agents such as VX and sarin Agrobacterium tumefaciens
environmental protection the enzyme is used for the detoxification of organophosphate pesticides and related chemical warfare agents such as VX and sarin Agrobacterium tumefaciens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetics Agrobacterium tumefaciens

Organism

Organism UniProt Comment Textmining
Agrobacterium tumefaciens Q93LD7 gene opdA
-

Reaction

Reaction Comment Organism Reaction ID
an aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol catalytic mechanism, the effects of substrate orientation on the mechanism of the enzyme, energetic parameters, overview Agrobacterium tumefaciens
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dimethoate + H2O
-
 Agrobacterium tumefaciens ?
-
 ?
methyl chlorpyrifos oxon + H2O
-
 Agrobacterium tumefaciens ?
-
 ?
methyl chlorpyrifos thion + H2O
-
 Agrobacterium tumefaciens ?
-
 ?
methyl paraoxon + H2O
-
 Agrobacterium tumefaciens 4-nitrophenol + dimethyl phosphate
-
 ?
methyl parathion + H2O
-
 Agrobacterium tumefaciens 4-nitrophenol + dimethyl thiophosphate
-
 ?
trimethyl phosphate + H2O
-
 Agrobacterium tumefaciens ?
-
 ?

Synonyms

Synonyms Comment Organism
OpdA
-
 Agrobacterium tumefaciens
phosphotriesterase
-
 Agrobacterium tumefaciens