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Literature summary for 3.1.8.1 extracted from

  • Bergmeier, C.; Siekmeier, R.; Gross, W.
    Distribution spectrum of paraoxonase activity in HDL fractions (2004), Clin. Chem., 50, 2309-2315.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
genotyping of PON1_192 and PON1_55 Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information naturally occurring polymorphism Q192R Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information the naturally occurring polymorphism Q192R has an effect on distribution profile of PON1 activity, while the L55M polymorphism has not, the enzyme activity is higher in the more dense HDL3 and VHDL fractions, quantification of apoprotein, overview Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
additional information the enzyme is not affected by phosphotungstic acid/MgCl2 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens HDL-associated enzyme is a cardio- and vasoprotective enzyme ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information HDL-associated enzyme is a cardio- and vasoprotective enzyme Homo sapiens ?
-
?
phenyl acetate + H2O
-
Homo sapiens phenol + acetate
-
?

Subunits

Subunits Comment Organism
More quantification of apoprotein, overview Homo sapiens

Synonyms

Synonyms Comment Organism
paraoxonase
-
Homo sapiens
PON1
-
Homo sapiens