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Literature summary for 3.1.8.1 extracted from

  • Herkenhoff, S.; Szinicz, L.; Rastogi, V.K.; Cheng, T.C.; DeFrank, J.J.; Worek, F.
    Effect of organophosphorus hydrolysing enzymes on obidoxime-induced reactivation of organophosphate-inhibited human acetylcholinesterase (2004), Arch. Toxicol., 78, 338-343.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Brevundimonas diminuta
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
paraoxon + H2O the enzyme prevents, independent of compound aging, the inhibition of acetylcholinesterase by paraoxon, and also by VX, sarin and soman, the latter are phosphyloxime products of acetlycholinesterase reaction with organophosphate inhibitors, overview Brevundimonas diminuta 4-nitrophenol + diethyl phosphate
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Synonyms

Synonyms Comment Organism
OPH
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Brevundimonas diminuta
organophosphorus hydrolase
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Brevundimonas diminuta