Any feedback?
Literature summary for 3.1.7.2 extracted from
- The guanosine 3,5-bis(diphosphate) (ppGpp) cycle. Comparison of synthesis and degradation of guanosine 3,5-bis(diphosphate) in various bacterial systems (1979), Eur. J. Biochem., 99, 57-64.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| ribosome | - |
Brevibacillus brevis | 5840 | - |
| ribosome | - |
Bacillus subtilis | 5840 | - |
| ribosome | - |
Escherichia coli | 5840 | - |
| ribosome | - |
Geobacillus stearothermophilus | 5840 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | activation | Bacillus subtilis |  |
| Co2+ | activation | Bacillus subtilis | |
| K+ | activation | Escherichia coli | |
| Mg2+ | activation | Bacillus subtilis | |
| Mn2+ | required | Escherichia coli | |
| Mn2+ | activation | Bacillus subtilis | |
| Mn2+ | activation | Escherichia coli | |
| NH4+ | activation | Escherichia coli | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 65000 | - |
sucrose density gradient centrifugation | Bacillus subtilis |
| 65000 | - |
sucrose density gradient centrifugation | Escherichia coli |
| 65000 | - |
sucrose density gradient centrifugation | Geobacillus stearothermophilus |
| 130000 | - |
dimeric enzyme form, gel filtration | Escherichia coli |
| 260000 | - |
tetrameric enzyme form, gel filtration | Escherichia coli |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ppGpp + H2O | Brevibacillus brevis | - |
ppG + diphosphate | - |
? | |
| ppGpp + H2O | Bacillus subtilis | - |
ppG + diphosphate | - |
? | |
| ppGpp + H2O | Escherichia coli | - |
ppG + diphosphate | - |
? | |
| ppGpp + H2O | Geobacillus stearothermophilus | - |
ppG + diphosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus subtilis | - |
- |
- |
| Brevibacillus brevis | - |
- |
- |
| Escherichia coli | - |
- |
- |
| Geobacillus stearothermophilus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ppGpp + H2O | - |
Brevibacillus brevis | ppG + diphosphate | - |
? | |
| ppGpp + H2O | - |
Bacillus subtilis | ppG + diphosphate | - |
? | |
| ppGpp + H2O | - |
Escherichia coli | ppG + diphosphate | - |
? | |
| ppGpp + H2O | - |
Geobacillus stearothermophilus | ppG + diphosphate | - |
? | |
| ppGpp + H2O | i.e. guanosine-3',5'-bis(diphosphate) | Brevibacillus brevis | ppG + diphosphate | i.e. guanosine 5'-diphosphate | ? | |
| ppGpp + H2O | i.e. guanosine-3',5'-bis(diphosphate) | Bacillus subtilis | ppG + diphosphate | i.e. guanosine 5'-diphosphate | ? | |
| ppGpp + H2O | i.e. guanosine-3',5'-bis(diphosphate) | Escherichia coli | ppG + diphosphate | i.e. guanosine 5'-diphosphate | ? | |
| ppGpp + H2O | i.e. guanosine-3',5'-bis(diphosphate) | Geobacillus stearothermophilus | ppG + diphosphate | i.e. guanosine 5'-diphosphate | ? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
