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Literature summary for 3.1.6.8 extracted from

  • Roy, A.B.
    Sulphatases, lysosomes and disease (1976), Aust. J. Exp. Biol. Med. Sci., 54, 111-135.
    View publication on PubMed
Search for more literature for 3.1.6.8

Application

Application Comment Organism
medicine
-
 Oryctolagus cuniculus
medicine deficiency in metachromatic leukodystrophy, a sphingolipid storage disorder Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
SO32- competitive inhibitor Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
100000
-
 sedimentation equilibrium ultracentrifugation Homo sapiens
107000
-
 at pH 7.5 Bos taurus
130000
-
 gel filtration Homo sapiens
140000
-
-
 Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cerebroside 3-sulfate + H2O Homo sapiens
-
 cerebroside + sulfate
-
 ?
cerebroside 3-sulfate + H2O Bos taurus
-
 cerebroside + sulfate
-
 ?
cerebroside 3-sulfate + H2O Oryctolagus cuniculus
-
 cerebroside + sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
-
-
Oryctolagus cuniculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-
liver
-
 Oryctolagus cuniculus
-
urine
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cerebroside 3-sulfate + H2O
-
 Homo sapiens cerebroside + sulfate
-
 ?
cerebroside 3-sulfate + H2O
-
 Bos taurus cerebroside + sulfate
-
 ?
cerebroside 3-sulfate + H2O
-
 Oryctolagus cuniculus cerebroside + sulfate
-
 ?

Subunits

Subunits Comment Organism
monomer at pH 5.6 monomer, at pH 4.8 tetramer Bos taurus
monomer 1 * 140000, each monomer consists of 2 equivalent polypeptide chains Oryctolagus cuniculus