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Literature summary for 3.1.6.4 extracted from

  • Yang, B.; Bhattacharyya, S.; Linhardt, R.; Tobacman, J.
    Exposure to common food additive carrageenan leads to reduced sulfatase activity and increase in sulfated glycosaminoglycans in human epithelial cells (2012), Biochimie, 94, 1309-1316.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.6.4

Organism

Organism UniProt Comment Textmining
Homo sapiens P34059
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Caco-2 cell
-
 Homo sapiens
-
colonocyte
-
 Homo sapiens
-
intestinal epithelium
-
 Homo sapiens
-
mammary epithelial cell
-
 Homo sapiens
-
MCF-10A cell
-
 Homo sapiens
-
MCF-7 cell
-
 Homo sapiens
-
NCM-460 cell
-
 Homo sapiens
-
T-47D cell
-
 Homo sapiens
-
T-84 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-methylumbelliferyl beta-D-galactoside 6-sulfate + H2O
-
 Homo sapiens 4-methylumbelliferyl beta-D-galactoside + sulfate
-
 ?

Synonyms

Synonyms Comment Organism
galactose-6-sulfatase
-
 Homo sapiens
GALNS
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens enzyme activity but not protein content declines after lambda-carrageenan exposure (0.001 mg/l for 48 h) down