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Literature summary for 3.1.6.4 extracted from
- Distinct effects of N-acetylgalactosamine-4-sulfatase and galactose-6-sulfatase expression on chondroitin sulfates (2008), J. Biol. Chem., 283, 9523-9530.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in MCF-7 cells. Following overexpression of the enzyme, total sulfated glycosaminoglycans, chondroitin 4-sulfate, and chondroitin sulfates decline significantly | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| lysosome | - |
Homo sapiens | 5764 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P34059 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GALNS | - |
Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.6 | - |
assay at | Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | deficiencies of N-acetylgalactosamine-6-sulfatase is associated with the mucopolysaccharidoses | Homo sapiens |
| metabolism | modification of expression of the enzyme regulates the content of chondroitin sulfate | Homo sapiens |
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Release 2023.1 (January 2023)
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