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Literature summary for 3.1.6.4 extracted from

  • Singh, J.; di Ferrante, N.; Niebes, P.; Tavella, D.
    N-Acetylgalactosamine-6-sulfate sulfatase in man. Absence of the enzyme in Morquio disease (1976), J. Clin. Invest., 57, 1036-1040.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine diagnosis of Morquio disease since extracts of Morquio fibroblasts are devoid of the enzyme Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
NaCl at high levels Homo sapiens
phosphate
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sulfated tetrasaccharide + H2O sulfated tetrasaccharide obtained by digestion of purified chondroitin 6-sulfate with resticular hyaluronidase Homo sapiens ?
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
4.8
-
-
Homo sapiens