BRENDA - Enzyme Database show
show all sequences of 3.1.6.3

Bacterial glycosulphatases and sulphomucin degradation

Robertson, A.M.; Wright, D.P.; Can. J. Gastroenterol. 11, 361-366 (1997)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
-
Prevotella sp.
5737
-
periplasm
-
Prevotella sp.
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Bacteroides thetaiotaomicron
-
-
-
Helicobacter pylori
-
-
-
Prevotella sp.
-
-
-
Ruminococcus torques
-
-
-
Ruminococcus torques IX-70
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
beta-galactosyl-6-O-sulfate (1-4)-glucitol + H2O
-
135644
Ruminococcus torques
beta-galactosyl-(1-4)glucitol
-
-
-
?
beta-galactosyl-6-O-sulfate (1-4)-glucitol + H2O
-
135644
Ruminococcus torques IX-70
beta-galactosyl-(1-4)glucitol
-
-
-
?
D-glucose-6-sulfate + H2O
-
135644
Helicobacter pylori
D-glucose + sulfate
-
-
-
?
D-glucose-6-sulfate + H2O
-
135644
Bacteroides thetaiotaomicron
D-glucose + sulfate
-
-
-
?
D-glucose-6-sulfate + H2O
-
135644
Prevotella sp.
D-glucose + sulfate
-
-
-
?
galactose-6-sulfate + H2O
-
135644
Helicobacter pylori
galactose + sulfate
-
-
-
?
N-acetyl-D-glucosamine 6-sulfate + H2O
-
135644
Helicobacter pylori
N-acetyl-D-glucosamine + sulfate
-
-
-
?
N-acetyl-D-glucosamine 6-sulfate + H2O
-
135644
Prevotella sp.
N-acetyl-D-glucosamine + sulfate
-
-
-
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
5
-
-
Bacteroides thetaiotaomicron
5
-
-
Ruminococcus torques
5.7
-
-
Helicobacter pylori
7
-
periplasm
Prevotella sp.
7.4
-
cytoplasm
Prevotella sp.
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
-
Prevotella sp.
5737
-
periplasm
-
Prevotella sp.
-
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
beta-galactosyl-6-O-sulfate (1-4)-glucitol + H2O
-
135644
Ruminococcus torques
beta-galactosyl-(1-4)glucitol
-
-
-
?
beta-galactosyl-6-O-sulfate (1-4)-glucitol + H2O
-
135644
Ruminococcus torques IX-70
beta-galactosyl-(1-4)glucitol
-
-
-
?
D-glucose-6-sulfate + H2O
-
135644
Helicobacter pylori
D-glucose + sulfate
-
-
-
?
D-glucose-6-sulfate + H2O
-
135644
Bacteroides thetaiotaomicron
D-glucose + sulfate
-
-
-
?
D-glucose-6-sulfate + H2O
-
135644
Prevotella sp.
D-glucose + sulfate
-
-
-
?
galactose-6-sulfate + H2O
-
135644
Helicobacter pylori
galactose + sulfate
-
-
-
?
N-acetyl-D-glucosamine 6-sulfate + H2O
-
135644
Helicobacter pylori
N-acetyl-D-glucosamine + sulfate
-
-
-
?
N-acetyl-D-glucosamine 6-sulfate + H2O
-
135644
Prevotella sp.
N-acetyl-D-glucosamine + sulfate
-
-
-
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
5
-
-
Bacteroides thetaiotaomicron
5
-
-
Ruminococcus torques
5.7
-
-
Helicobacter pylori
7
-
periplasm
Prevotella sp.
7.4
-
cytoplasm
Prevotella sp.
Other publictions for EC 3.1.6.3
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
655716
Macfarlane
Toxin synthesis and mucin brea ...
Clostridium septicum
Infect. Immun.
69
1120-1126
2001
-
-
-
-
-
-
1
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
135644
Robertson
Bacterial glycosulphatases and ...
Bacteroides thetaiotaomicron, Helicobacter pylori, Prevotella sp., Ruminococcus torques, Ruminococcus torques IX-70
Can. J. Gastroenterol.
11
361-366
1997
-
-
-
-
-
-
-
-
2
-
-
-
-
6
-
-
-
-
-
-
-
-
8
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
8
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
135639
Roberton
-
A glycosulphatase that removes ...
Prevotella sp., Prevotella sp. RS2
Biochem. J.
293
683-689
1993
-
-
-
-
-
1
3
1
1
-
2
-
-
3
-
-
1
-
-
1
1
1
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
1
1
-
2
-
-
-
-
1
-
1
1
1
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
135641
Slomiany
Glycosulfatase activity of Por ...
Porphyromonas gingivalis
Biochem. Mol. Biol. Int.
29
973-980
1993
-
-
-
-
-
-
-
-
1
-
1
-
-
3
-
-
1
-
-
-
-
-
2
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
1
-
-
-
-
2
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
135643
Slomiany
Glycosulfatase activity of Hel ...
Helicobacter pylori
J. Physiol. Pharmacol.
44
7-16
1993
2
-
-
-
-
-
1
-
1
-
1
-
-
3
-
-
-
-
-
-
-
-
3
1
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
-
-
-
-
3
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
135640
Corfield
Mucin degradation in the human ...
Bifidobacterium sp., Bifidobacterium sp. VIII-210, Bifidobacterium sp. VIII-240, Ruminococcus torques, Ruminococcus torques IX-70, Ruminococcus torques VIII-239
Infect. Immun.
60
3971-3978
1992
-
-
-
-
-
-
-
-
-
-
-
-
-
10
-
-
-
-
-
4
4
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
4
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
135642
Slomiany
Glycosulfatase activity of Hel ...
Helicobacter pylori
Biochem. Biophys. Res. Commun.
183
506-513
1992
2
-
-
-
-
-
-
-
1
-
-
-
-
3
-
-
-
-
-
1
1
-
6
-
-
-
-
-
1
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
1
-
6
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
135638
Roy
The sulphatase of ox liver. XX ...
Bos taurus
Biochim. Biophys. Acta
704
366-373
1982
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
135637
McLean
Glycosulphatase from Pseudomon ...
Pseudomonas carrageenovora
Eur. J. Biochem.
101
497-505
1979
-
-
-
-
-
-
1
1
1
-
1
-
-
1
-
-
1
-
-
-
-
-
2
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
1
-
1
-
-
-
-
1
-
-
-
-
2
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
135630
Hatanaka
Two glycosulfatases from the l ...
Charonia lampas
J. Biochem.
79
27-34
1976
-
-
-
-
-
-
2
1
-
-
2
-
-
2
-
1
1
-
-
1
1
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
1
-
-
2
-
-
-
1
1
-
1
1
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
135631
Hatanaka
Arylsulphatase and glycosulpha ...
Charonia lampas
Biochem. J.
159
445-448
1976
-
-
-
-
-
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
135632
Hatanaka
Sulfatide and seminolipid as s ...
Charonia lampas
J. Biochem.
78
427-429
1975
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
135636
Lloyd
-
Desulphation of L-fucose monos ...
Patella vulgata
Biochem. J.
124
21
1971
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
135633
Lloyd
The glycosulphatase of Trichod ...
Trichoderma viride
Biochem. J.
108
393-399
1968
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
1
3
-
1
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
3
-
1
1
-
-
1
1
-
-
-
-
-
-
-
-
135635
Lloyd
-
Deactivation of glycosulphatas ...
Patella vulgata
Biochem. J.
107
7-7
1968
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
135634
Lloyd
-
Separation of glycosulphatase ...
Patella vulgata
Biochem. J.
165
33-34
1967
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
135629
Lloyd
-
Glucosulfatases from molluscs ...
Charonia lampas, Littorina littorea
Methods Enzymol.
8
670-677
1966
-
-
-
-
-
-
5
2
-
2
-
-
-
2
-
-
1
-
-
2
1
-
7
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
2
-
2
-
-
-
-
-
1
-
2
1
-
7
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-