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Literature summary for 3.1.6.21 extracted from

  • Kida, Y.; Yamamoto, T.; Kuwano, K.
    SdsA1, a secreted sulfatase, contributes to the in vivo virulence of Pseudomonas aeruginosa in mice (2020), Microbiol. Immunol., 64, 280-295 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
mucin + H2O Pseudomonas aeruginosa
-
? + sulfate
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa Q9I5I9
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
mucin + H2O
-
Pseudomonas aeruginosa ? + sulfate
-
?

Synonyms

Synonyms Comment Organism
sdsA1
-
Pseudomonas aeruginosa

General Information

General Information Comment Organism
malfunction the sdsA1 mutant shows a reduction in the ability of mucin gel penetration and an attenuation of virulence in leukopenic mice compared with the wild type strain Pseudomonas aeruginosa
physiological function the enzyme plays an important role as a virulence factor of Pseudomonas aeruginosa Pseudomonas aeruginosa