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Literature summary for 3.1.6.2 extracted from

  • Mutembei, H.M.; Kowalewski, M.P.; Ugele, B.; Schuler, G.; Hoffmann, B.
    Expression and activity of steroid sulphatase in the boar testis (2009), Reprod. Domest. Anim., 44, 17-23.
    View publication on PubMed
Search for more literature for 3.1.6.2

Cloned(Commentary)

Cloned (Comment) Organism
partial sequence of porcine StS, subcloned into pGEM T vector, amplified in Escherichia coli Sus scrofa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00215
-
 Estrone sulfate 37°C, 10 min reaction time, Ringer-HEPES buffer, Vmax=24.05 fmol/s/microgram protein Sus scrofa

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Sus scrofa 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
estrone sulfate + H2O Sus scrofa STS within the Leydig cells of Sus scrofa is involved in modulation of testicular estrogen bioavailability estrone + sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Sus scrofa Q45FD5 Sus scrofa steroid sulfatase (StS) mRNA, partial cds from boar testis; 5 age groups 50, 100, 150, 250 days old boars, remarkably high testicular estrogen output
-

Source Tissue

Source Tissue Comment Organism Textmining
Leydig cell all cells with positive StS expression,exception: 65.1% StS expression in 50-day-old animal's Leydig cells Sus scrofa
-
testis
-
 Sus scrofa
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
estrone sulfate + H2O
-
 Sus scrofa estrone + sulfate
-
 ?
estrone sulfate + H2O STS within the Leydig cells of Sus scrofa is involved in modulation of testicular estrogen bioavailability Sus scrofa estrone + sulfate
-
 ?

Synonyms

Synonyms Comment Organism
steroid sulfatase
-
 Sus scrofa
STS
-
 Sus scrofa