Activating Compound | Comment | Organism | Structure |
---|---|---|---|
glutathione | oxidized form, 5 mM, 187% of initial activity | Homo sapiens | |
L-beta-phenylalanine | 5 mM, 169% of initial activity | Homo sapiens | |
L-cysteine | 5 mM, 202% of initial activity | Homo sapiens | |
lithocholic acid | 5 mM, 226% of initial activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ammonium molybdate | 10 mM, 20% residual activity | Homo sapiens | |
calcium chloride | 5 mM, 36% residual activity | Homo sapiens | |
dithiothreitol | 5 mM, 45% residual activity | Homo sapiens | |
glutathione | reduced form, 5 mM, 23.5% residual activity | Homo sapiens | |
additional information | not inhibitory: phosphate, sulfate, sulfide | Homo sapiens | |
vanadium oxide(V) | 50 mM, 51% residual activity | Homo sapiens | |
Zinc acetate | 1.25 mM, 53% residual activity | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.033 | - |
dehydroepiandrosterone 3-sulfate | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
62000 | - |
x * 62000, SDS-PAGE | Homo sapiens |
74000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
enzyme does not copurify with oestrone sulfate sulfohydrolase | - |
Purification (Comment) | Organism |
---|---|
enzyme does not copurify with oestrone sulfate sulfohydrolase | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.52 | - |
- |
Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dehydroepiandrosterone 3-sulfate + H2O | - |
Homo sapiens | dehydroepiandrosterone + sulfate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 62000, SDS-PAGE | Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
60 | - |
5 min, 115% resiudal activity | Homo sapiens |
80 | - |
5 min, 100% residual activity | Homo sapiens |
100 | - |
5 min, 87% residual activity | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.4 | - |
- |
Homo sapiens |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Homo sapiens | isoelectric focusing | - |
8.7 |