Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bovine serum albumin | - |
Homo sapiens | |
CN- | - |
Homo sapiens | |
Hg2+ | - |
Homo sapiens | |
PO43- | - |
Homo sapiens | |
S2O32- | - |
Homo sapiens | |
SO32- | - |
Homo sapiens | |
SO42- | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.15 | - |
trisaccharide with an N-acetylglucosamine 6-sulfate residue | - |
Homo sapiens | |
7.7 | - |
glucose 6-sulfate | - |
Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
97000 | - |
gel filtration | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-D-glucosamine 6-sulfate units + H2O | Homo sapiens | in oligo-and monosaccharides derived from heparan sulfate and keratan sulfate | N-acetyl-D-glucosamine units + sulfate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | - |
Homo sapiens |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
liver | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
skin fibroblast | in culture | Homo sapiens | - |
spleen | - |
Homo sapiens | - |
telencephalon | - |
Homo sapiens | - |
urine | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glucose 6-sulfate + H2O | - |
Homo sapiens | glucose + sulfate | - |
? | |
N-acetyl-D-glucosamine 6-sulfate + H2O | higher activity in liver compared to trisaccharides | Homo sapiens | N-acetyl-D-glucosamine + sulfate | - |
? | |
N-acetyl-D-glucosamine 6-sulfate units + H2O | catalyzes hydrolysis of sulfate from internal N-acetylglucosamine 6-sulfate at a lower rate | Homo sapiens | N-acetyl-D-glucosamine units + sulfate | - |
? | |
N-acetyl-D-glucosamine 6-sulfate units + H2O | in substrates bearing a N-acetylglucosamine 6-sulfate residue at its nonreducing terminus derived from heparan sulfate and keratan sulfate | Homo sapiens | N-acetyl-D-glucosamine units + sulfate | - |
? | |
N-acetyl-D-glucosamine 6-sulfate units + H2O | specific exosulfatase for desulfation of the nonreducing terminal N-acetylglucosamine 6-sulfate residues of heparansulfate | Homo sapiens | N-acetyl-D-glucosamine units + sulfate | - |
? | |
N-acetyl-D-glucosamine 6-sulfate units + H2O | has no activity towards heparin, heparansulfate and keratansulfate, increase of activity in monosulfated tetra- or trisaccharides, maximum activity in sulfated monosaccharides | Homo sapiens | N-acetyl-D-glucosamine units + sulfate | - |
? | |
N-acetyl-D-glucosamine 6-sulfate units + H2O | in oligo-and monosaccharides derived from heparan sulfate and keratan sulfate | Homo sapiens | N-acetyl-D-glucosamine units + sulfate | - |
? | |
trisaccharide derived from heparansulfate with a N-acetylglucosamine 6-sulfate residue + H2O | lower activity in liver compared to monosaccharides | Homo sapiens | trisaccharide with a N-acetylglucosamine + sulfate | - |
? | |
trisaccharide with an N-acetylglucosamine 6-sulfate residue + H2O | - |
Homo sapiens | trisaccharide with an N-acetylglucosamine + sulfate | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
70 | - |
after 3 min 70% loss of activity | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.5 | - |
trisaccharide | Homo sapiens |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
5 | 7.5 | - |
Homo sapiens |