Literature summary for 3.1.6.12 extracted from

Zhang, J.; Liang, H.; Zhu, L.; Gan, W.; Tang, C.; Li, J.; Xu, R.
Expression and distribution of arylsulfatase B are closely associated with neuron death in SOD1 G93A transgenic mice (2018), Mol. Neurobiol., 55, 1323-1337 .

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P50429	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
spinal cord	ARSB is extensively expressed and distributed in the entire spinal cord. Expression in anterior horn of gray matter is significantly higher than that in the posterior horn of gray matter and significantly higher than that in the central canal. ARSB is mainly distributed in the microglia and neuron cells in the wild-type mice	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
ARSB	-	Mus musculus

General Information

General Information	Comment	Organism
physiological function	abnormal expression and distribution of ARSB are closely associated with the neuron death in the superoxide dismutase mutant G93A transgenic mice. ARSB participates in the pathogenesis of amyotrophic lateral sclerosis (ALS), the relative deficiency of ARSB expression and redistribution in the anterior horn of gray matter and the posterior horn of gray matter of spinal cord in ALS-like superoxide dismutase G93A transgenic mice is closely associated with the neuron death	Mus musculus

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Release 2023.1 (January 2023)