Literature summary for 3.1.6.12 extracted from

Bhattacharyya, S.; Feferman, L.; Tobacman, J.K.
Arylsulfatase B regulates versican expression by galectin-3 and AP-1 mediated transcriptional effects (2013), Oncogene, 33, 5467-5476.

Search for more literature for 3.1.6.12

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P34059	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
prostate	prostrate stromal and epithelial cells	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	in human prostate stromal and epithelial cells, when arylsulfatase B is silenced, chondroitin-4-sulfate, versican and versican promoter activity increase, and the galectin-3 that co-immunoprecipitates with chondroitin-4-sulfate declines. Galectin-3 silencing inhibits the arylsulfatase B-silencing-induced increases in versican and versican promoter due to effects on the AP-1-binding site in the versican promoter	Homo sapiens

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Release 2023.1 (January 2023)